Fungal Toenail infection in 59 y/o woman
Previous trauma (stepped on by horse, dropped large object on, etc.) to toe over a period of 15-20 years resulting in pressure build-up requiring drilling and subsequent loss of complete toenail 3 times.
Patient was treated with various topical and oral antifungal medications with minimal improvement. Laser was performed in 2017 with minimal improvement as well.
Patient had PCR nail panel performed in September 2020.
She was seen for evaluation by 2 separate podiatrists. Podiatrist 1 dismissed test results and recommended laser treatment.
Patient sought second opinion based on failure of laser treatment in 2017 and lack of insurance coverage for the $890 therapy.
Podiatrist 2 was very happy with completeness of PCR panel and stated the nail could be cleared with a combination of oral and topical medication, based on the report, but stated the patient would still be left with a deformed, unsightly nail due to the length of infection duration resulting in curvature of the nail root.
Early PCR Testing Leads to Better Outcome
Podiatrist 2 stated that with PCR result early in trauma/infection, nail could have been treated effectively and saved.
Patient opted for nail removal which is scheduled for mid-October, 2020.
Molecular Diagnostics with PCR testing
In this case, it is likely that had PCR testing been done earlier, the patient could have been treated with the right oral and topical meds for the specific infection and saved the toenail.
Oral and topical meds only have low success rates because patients are treated empirically without knowing the actual infectious organisms.
PCR testing earlier in the course of the infection may have saved the nail
Real Time Polymerase Chain Reaction (RT PCR)
Real Time Polymerase Chain Reaction (PCR) infectious disease testing offers
higher accuracy and broader detection than culture.
▪ Detects the presence of infection by amplifying pathogen RNA and DNA
▪ Pathogen and antibiotic resistance information in 24 hours
▪ Increased sensitivity and specificity
▪ Unaffected by concurrent use of antibiotics
▪ Identifies polymicrobial infections
Identifying cause of infection on the first test is important especially in immunocompromised patients, including the elderly.
Here's what you need in your practice:
- PCR testing that provides causative microbe coverage for up to 99% of syndrome-related
microbes, some of which are not detected by traditional culture and sensitivity.
- The test panels that offer information on the antibiotic resistance genes found in an individual sample. This information can help the clinician choose the best possible anti-infective therapy for the patient.
Get Up to 99% detection of causative bacterial, viral, fungal pathogens with sensitivity reports
Get Advanced PCR Testing For Your Practice
Your patients want an answer. "What do I have?"
Especially when point of care testing is not available, inconclusive, or doesn't give you an actual treatment decision, as well as for confirmation, rapid turn-around PCR testing (24-36h) will keep your patients safe, out of the hospital, and your reputation intact.
"The urgent care mis-diagnosed me" is not something you want to see on your online reviews.
Let's get this set up in your practice: